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2 Dong XH, Gao WJ, Kong WN, Xie HL, Peng Y, Shao TM, Yu WG, Chai XQ. (2015) Neuroprotective effect of the active components of three Chinese herbs on brain iron load in a mouse model of Alzheimer’s disease. Exp Ther Med. 2015 Apr;9(4):1319-1327.

3 Yao H, Gu LJ, Guo JY. (2014) Study on effect of astragali radix polysaccharides in improving learning and memory functions in aged rats and its mechanism. Zhongguo Zhong Yao Za Zhi. 2014 Jun;39(11):2071-5.

4 Zhong L, Wang ZF, Wen DJ. (2013) Experimental research on the anti-aging effects of astragalus polysaccharides. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Jul;29(4):350-2.

5 Zhang H, Pan N, Xiong S, Zou S, Li H, Xiao L, Cao Z, Tunnacliffe A, Huang Z. (2012) Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans. Biochem J. 2012 Jan 1;441(1):417-24

6 Li W, Li W, Yin Y, Gong H, Wu G, Zhu F. (2009) Protective effects of AST and ASI on memory impairment and its mechanism in senescent rats treated by GC. Zhongguo Zhong Yao Za Zhi. 2009 Jan;34(2):199-203.

7 Li WZ, Li WP, Yin YY. (2007)Effects of AST and ASI on metabolism of free radical in senescent rats treated by HC. Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(23):2539-42.

8 Lei H, Wang B, Li WP, Yang Y, Zhou AW, Chen MZ. (2003) Anti-aging effect of astragalosides and its mechanism of action. Acta Pharmacol Sin. 2003 Mar;24(3):230-4.

9 Li XT, Zhang YK, Kuang HX, Jin FX, Liu DW, Gao MB, Liu Z, Xin XJ (2012) Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism. Int J Mol Sci. 2012;13(2):1747-61

10 Fu S, Gu Y, Jiang JQ, Chen X, Xu M, Chen X, Shen J. (2014) Calycosin-7-O-β-D-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood-brain barrier integrity in experimental cerebral ischemia-reperfusion injury. J Ethnopharmacol. 2014 Aug 8;155(1):692-701.

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12 Shi R, He L, Hu Y, Yi N, Weng S, Cao Y. (2001) The regulatory action of Radix Astragali on M-cholinergic receptor of the brain of senile rats. J Tradit Chin Med. 2001 Sep;21(3):232-5.

13 Yan M, Song H, Xie N, Zhang L. (1995) Changes of intestinal flora in senile mouse models and the antagonistic activity of the root of Astragalus membraceus (Fisch) Bge. Zhongguo Zhong Yao Za Zhi. 1995 Oct;20(10):624-6, inside backcover.

14 Hsu MF, Chiang BH. (2009) Stimulating effects of Bacillus subtilis natto-fermented Radix astragali on hyaluronic acid production in human skin cells. J Ethnopharmacol. 2009 Sep 25;125(3):474-81.

15 Chen B, Li R, Yan N, Chen G, Qian W, Jiang HL, Ji C, Bi ZG. (2015) Astragaloside IV controls collagen reduction in photoaging skin by improving transforming growth factor-β/Smad signaling suppression and inhibiting matrix metalloproteinase-1. Mol Med Rep. 2015 May;11(5):3344-8

16 Hong MJ, Ko EB, Park SK, Chang MS. (2012) Inhibitory effect of Astragalus membranaceus root on matrix metalloproteinase-1 collagenase expression and procollagen destruction in ultraviolet B-irradiated human dermal fibroblasts by suppressing nuclear factor kappa-B activity. J Pharm Pharmacol. 2013 Jan;65(1):142-8.

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18 Yung LY1, Lam WS, Ho MK, Hu Y, Ip FC, Pang H, Chin AC, Harley CB, Ip NY, Wong YH. (2012) Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types. Planta Med. 2012 Jan;78(2):115-21.

19 Molgora B, Bateman R, Sweeney G, Finger D, Dimler T, Effros RB, Valenzuela HF (2013) Functional assessment of pharmacological telomerase activators in human T cells.Cells. 2013 Jan 14;2(1):57-66.

20 Bernardes de Jesus B, Schneeberger K, Vera E, Tejera A, Harley CB, Blasco MA. (2011) The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell. 2011 Aug;10(4):604-21.

21 Mendelsohn AR, Larrick JW. (2012) Ectopic expression of telomerase safely increases health span and life span. Rejuvenation Res. 2012 Aug;15(4):435-8.

22 Børge G. NordestgaardStig E. Bojesen Line Rode (2015) Peripheral Blood Leukocyte Telomere Length and Mortality Among 64 637 Individuals From the General Population JNCI J Natl Cancer Inst (2015) 107(6)

23 Richard M Cawthon,Ken R Smith,Elizabeth O’BrienAnna SivatchenkoRichard A Kerber, (2003)  Association between telomere length in blood and mortality in people aged 60 years or older

Lancet Volume 361, Issue 9355, 1 February 2003, Pages 393–395

24 Wang P, Zhang Z, Sun Y, Liu X, Tong T. (2010) The two isomers of HDTIC compounds from Astragali Radix slow down telomere shortening rate via attenuating oxidative stress and increasing DNA repair ability in human fetal lung diploid fibroblast cells. DNA Cell Biol. 2010 Jan;29(1):33-9.

25 Wang PC, Zhang ZY, Zhang J, Tong TJ. (2008) Two isomers of HDTIC isolated from Astragali Radix decrease the expression of p16 in 2BS cells.Chin Med J (Engl). 2008 Feb 5;121(3):231-5.

26 Li WZ1, Li WP, Yin YY. (2007) Effects of AST and ASI on metabolism of free radical in senescent rats treated by HC. Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(23):2539-42. 


1 877 545-1999 (Fr)

1 418 246-1999 (Fr)

1 833 236-1999 (En)